Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Article Title: Implementation of inpatient models of pharmacogenetics programs

doi: 10.2146/ajhp150946

Figure Lengend Snippet: Comparison of Pharmacogenetic Practice Models at Three Institutions a

Article Snippet: Genotype platform and alleles detected , eSensor XT-8 (GenMark Diagnostics, Carlsbad, CA) CYP2C19*2, CYP2C19*3, CYP2C19*4, CYP2C19*5, CYP2C19*6, CYP2C19*8, CYP2C19*17 , eSensor XT-8 (GenMark Diagnostics) VKORC1 c.-1639G>A; CYP4F2 1347G>A (V433M); CYP2C9*2, CYP2C9*3, CYP2C9*5, CYP2C9*6, CYP2C9*11, CYP2C9*14, CYP2C9*15, CYP2C9*16; CYP2C19*2, CYP2C19*3, CYP2C19*4, CYP2C19*5, CYP2C19*6, CYP2C19*8, CYP2C19*17 , TaqMan (Life Technologies, Foster City, CA) CYP2C19*2, CYP2C19*3, CYP2C19*17.

Techniques:

Journal: Pharmacogenomics

Article Title: Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation

doi: 10.2217/pgs.12.2

Figure Lengend Snippet: US FDA warning label for clopidogrel and warfarin and FDA-approved testing platforms and assays for the analyte(s).

Article Snippet: GenMark Diagnostics eSensor ® XT-8 System (DNA Genotek Oragene-Dx collection device) , December 2011.

Techniques: Biomarker Assay, Genotyping Assay

Journal: Clinical pharmacology and therapeutics

Article Title: Multi-site investigation of strategies for the implementation of CYP2C19 genotype-guided antiplatelet therapy

doi: 10.1002/cpt.1006

Figure Lengend Snippet: Pharmacogenomic testing

Article Snippet: Median genotype turnaround time (TAT), defined as each institution’s median time from genotype order to result appearing in the EHR, varied widely among institutions, from very short (1 to 5 hours with rapid testing platforms such as Spartan RX), to 1-3 days with standard single-gene test platforms in reactive models (GenMark eSensor XT-8 or custom Taqman® assays), to longer (6 to 8 days) for those institutions who used preemptive panel-based or send-out testing strategies.

Techniques: TaqMan Assay

Journal: Principles and Practice of Transplant Infectious Diseases

Article Title: Viral Diagnostics

doi: 10.1007/978-1-4939-9034-4_49

Figure Lengend Snippet: Respiratory viruses (FDA cleared and commercially available)

Article Snippet: eSensor RVP (GenMark dx) , XT-8. Tat 5.5 hrs , NP swabs & throat swabs , 99.2%/ 99.7% , IVD , XT-8 System Detection; TAT 6.0 hrs (12 viruses) , NP swabs and throat swabs , 99.2%/99.7% , IVD.

Techniques: Luminex, Real-time Polymerase Chain Reaction, Cell Culture, Nested PCR

Journal: Clinics in Laboratory Medicine

Article Title: Molecular Detection of Respiratory Viruses

doi: 10.1016/j.cll.2013.03.007

Figure Lengend Snippet: GenMark eSensor system. ( A ) XT-8 instrument. ( B ) eSensor cartridge. Instrument footprint in inches: 15.75 width × 18.11 height × 16.14 depth. A computer is not required for operation.

Article Snippet: GenMark eSensor system. ( A ) XT-8 instrument. ( B ) eSensor cartridge.

Techniques:

Journal: Principles and Practice of Transplant Infectious Diseases

Article Title: Viral Diagnostics

doi: 10.1007/978-1-4939-9034-4_49

Figure Lengend Snippet: Respiratory viruses (FDA cleared and commercially available)

Article Snippet: eSensor RVP (GenMark dx) , XT-8. Tat 5.5 hrs , NP swabs & throat swabs , 99.2%/ 99.7% , IVD , XT-8 System Detection; TAT 6.0 hrs (12 viruses) , NP swabs and throat swabs , 99.2%/99.7% , IVD.

Techniques: Luminex, Virus, Real-time Polymerase Chain Reaction, Cell Culture, Bacteria, Nested PCR

Journal: Advances in Molecular Pathology

Article Title: Syndromic and Point-of-Care Molecular Testing

doi: 10.1016/j.yamp.2018.07.007

Figure Lengend Snippet: The ePlex ( A ), ePlex NP ( B ), and eSensor XT-8 ( C ) systems available from GenMark Diagnostics. Also shown are examples of ePlex ( D ) and XT-8 ( E ) panels. The nucleic acid hybridization complex described in the text is shown in ( F ).

Article Snippet: The ePlex, ePlex NP, and XT-8 systems (GenMark Diagnostics, Inc., Carlsbad, CA; ) use patented eSensor technology to detect a variety of pathogens directly from patient specimens (ePlex and ePlex NP systems) and amplified nucleic acid mixtures (eSensor XT-8 system).

Techniques: Nucleic Acid Hybridization

Journal: Advances in Molecular Pathology

Article Title: Syndromic and Point-of-Care Molecular Testing

doi: 10.1016/j.yamp.2018.07.007

Figure Lengend Snippet: The ePlex ( A ), ePlex NP ( B ), and eSensor XT-8 ( C ) systems available from GenMark Diagnostics. Also shown are examples of ePlex ( D ) and XT-8 ( E ) panels. The nucleic acid hybridization complex described in the text is shown in ( F ).

Article Snippet: The ePlex ( A ), ePlex NP ( B ), and eSensor XT-8 ( C ) systems available from GenMark Diagnostics.

Techniques: Nucleic Acid Hybridization

Journal: Advances in Molecular Pathology

Article Title: Syndromic and Point-of-Care Molecular Testing

doi: 10.1016/j.yamp.2018.07.007

Figure Lengend Snippet: Syndromic Panels that Are Currently Available in the United States for the Detection of Upper Respiratory Tract Pathogens

Article Snippet: The ePlex ( A ), ePlex NP ( B ), and eSensor XT-8 ( C ) systems available from GenMark Diagnostics.

Techniques: Virus